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Premenstrual Disphoric Disorder, PMS & PMDD Treatment

What is PMDD?

PMDD is a medical condition that affects millions of women. The symptoms of PMDD usually show up one to two weeks before menstrual periods or cycles. They include irritability, mood swings, tension, bloating, and breast tenderness. Symptoms of PMDD are often so bad they interfere with daily activities and often lead to psychological impairment.

What is Sarafem?

Sarafem is a prescription medication used by women to treat symptoms of premenstrual dysphoric disorder (PMDD).

How does Sarafem work to relieve symptoms?

Sarafem works exactly like Prozac, the commonly prescribed medication used to treat depression. Safafem helps balance levels of serotonin in the brain. Many doctors now believe that PMDD is directly related to an imbalance of serotonin. By restoring levels of serotonin Sarafem improves the symptoms of PMDD.

How do I take Sarafem?

Sarafem comes in easy to swallow 10 mg or 20 mg tablets. It's important that you take Sarafem exactly as directed by your doctor in order to avoid any complications. The most common prescribed dose is 20 mg a day. If you happen to miss a dose, take it as soon as you remember. However, if it's near the time for your next dose, skip it and continue with your schedule. Consult with your doctor about the length of treatment or if you plan to stop using Sarafem anytime soon.

What should I tell my doctor before I begin taking Sarafem?

Before you begin taking Sarafem, make sure that your doctor knows about any anti depressant medications you are currently on. Also, make your doctor aware of any herbal remedies, vitamins, natural supplements, and herbal remedies you are using. Tell your doctor if you have diabetes, liver disease, or a history of seizures or mania. Additionally, let your doctor know if you plan to become pregnant, are currently pregnant, or if you're nursing.

When can I expect to get relief from symptoms?

You should start experiencing a decrease in irritability, mood swings, tension, bloating, and breast tenderness by the next menstral period.

What are some possible side effects of Sarafem?

While taking Sarafem you may experience side effects. Side effects of Sarafem are generally mild, and often disappear within a few weeks. Common side effects experienced by women include: tiredness, upset stomach, nervousness, dizziness, and difficulty concentrating.

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Directions

Take this medication by mouth usually once daily in the morning, with or without food; or as directed by your doctor. The dosage is based on your medical condition and response to therapy. Some medical conditions may require a different dosing schedule (e.g., twice daily in the morning and at noon) as determined by your doctor. Take this medication exactly as prescribed. It is important to continue taking this medication even if you feel well. Also, do not stop taking this medication without consulting your doctor. It may take up to 4 weeks before the full benefit of this drug takes effect.

Patient information

Nausea, headache, trouble sleeping, dry mouth, drowsiness, sweating, or upset stomach may occur. If any of these effects persist or worsen, notify your doctor promptly. Tell your doctor immediately if any of these serious side effects occur: loss of appetite, unusual weight loss, unusual or severe mental/mood changes, uncontrolled movements (tremor), decreased interest in sex, flu-like symptoms (e.g., chills, fever, muscle aches, weakness). Tell your doctor immediately if any of these unlikely but serious side effects occur: vision changes, trouble swallowing, swelling or white spots on the mouth and/or tongue, changes in sexual ability, painful and/or prolonged erection. Tell your doctor immediately if any of these highly unlikely but very serious side effects occur: fainting, irregular/fast heartbeat. An allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.

Precautions

Tell your doctor your medical history, especially of: liver problems, kidney disease, seizures, heart problems, diabetes, any allergies. This drug may make you dizzy or drowsy; use caution engaging in activities requiring alertness such as driving or using machinery. Limit alcoholic beverages. Liquid preparations of this product may contain sugar and/or small amounts of alcohol. Caution is advised if you have diabetes, alcohol dependence, or liver disease. Ask your doctor or pharmacist about the safe use of this product. Caution is advised when using this product in the elderly because they may be more sensitive to the effects of the drug. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug passes into breast milk. Because of the potential risk to the infant, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

Drug interactions

Certain medications taken with this product could result in serious, even fatal, drug interactions. Avoid taking MAO inhibitors (e.g., furazolidone, isocarboxazid, linezolid, moclobemide, phenelzine, procarbazine, selegiline, tranylcypromine) within 2 weeks, and avoid taking thioridazine within 5 weeks, before or after treatment with this medication. Consult your doctor or pharmacist for additional information. This drug is not recommended for use with: weight loss medicine (e.g., sibutramine, phentermine), thioridazine, terfenadine, astemizole. Ask your doctor or pharmacist for more details. Tell your doctor of all prescription and non- prescription medication you may use, especially: other SSRI antidepressants (e.g., citalopram, sertraline), nefazodone, trazodone, venlafaxine, "triptan" migraine drugs (e.g., sumatriptan, zolmitriptan), tramadol, tricyclic antidepressants (e.g., amitriptyline, nortriptyline), flecainide, propafenone, haloperidol, clozapine, lithium, tryptophan, "blood thinners" (e.g., warfarin), anti-seizure drugs (e.g., carbamazepine, phenytoin/hydantoins), herbal/natural products (e.g., St John's wort, ayahuasca). Tell your doctor if you take any drugs that cause drowsiness such as: medicine for sleep, tranquilizers, anti-anxiety drugs (e.g., alprazolam), narcotic pain relievers (e.g., codeine), muscle relaxants, psychiatric medicine (e.g., henothiazines such as chlorpromazine), certain antihistamines (e.g.,diphenhydramine). Check the labels on all your medicines (e.g., cough-and- cold products) because they may contain drowsiness-causing ingredients. Ask your pharmacist about the safe use of these products. Report other drugs which affect the heart rhythm (QTc prolongation), such as: dofetilide, pimozide, sotalol, quinidine, procainamide,parfloxacin, "water pills" (diuretics such as furosemide or hydrochlorothiazide). Ask your doctor or pharmacist for more details. Fluoxetine may affect the amount of glucose (sugar) in your blood. If you take any anti-diabetes medication (e.g., glipizide, glyburide, metformin), your dosage of these drugs may need to be adjusted when fluoxetine is started or discontinued. Consult your doctor. Do not start or stop any medicine without doctor or pharmacist approval.


 
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